The Institute has two-tier management structure.

Board of Directors

Chairman, North Eastern Council Chairman
Minister of Health & Family Welfare, Assam Member
Chairman, Atomic Energy Commission& Secretary, Department of Atomic Energy, Govt. of India Member
Secretary, Ministry of Health & F.W., Govt. of India Member
Secretary, DONER, Govt. of India, New Delhi Member
Secretary, North Eastern Council Secretariat, Shillong Member
One nominee of the B Borooah Cancer Society Trust Member
Chairperson of the Management Council of the Institute Member
Director, Dr B Borooah Cancer Institute Member Secretary
Management Council

Director, Tata Memorial Centre, Mumbai Chairman
Secretary, Health & Family Welfare Department,Govt. of Assam (or his representative) Member
Nominee of Secretary, Health & F.W., Govt. of India Member
Two representatives of North Eastern Council, Shillong Member
One representative of the Director General of Health Services, Govt. of India, New Delhi Member
Joint Secretary (R&D), Department of Atomic Energy, Govt. of India. Member
Three nominees of Board of Trustees, BBCI Member
Representative of State Govt. of NE states except Assam not below the rank of Joint Secretary or Additional Director (Health) - 2 States by rotation for one year at a time. Members
Joint Secretary (NEC), DONER, Govt. of India
(or his / her representative)
Director of the Institute Member Secretary
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